Category Archives: Mutation

Mutations are changes in a genomic sequence: the DNA sequence of a cell’s genome or the DNA or RNA sequence of a virus. Mutations are caused by radiation, viruses, transposons and mutagenic chemicals, as well as errors that occur during meiosis or DNA replication. They can also be induced by the organism itself, by cellular processes such as hypermutation.

Mutation can result in several different types of change in DNA sequences; these can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Studies in the fly Drosophila melanogaster suggest that if a mutation changes a protein produced by a gene, this will probably be harmful, with about 70 percent of these mutations having damaging effects, and the remainder being either neutral or weakly beneficial. Due to the damaging effects that mutations can have on cells, organisms have evolved mechanisms such as DNA repair to remove mutations. Therefore, the optimal mutation rate for a species is a trade-off between costs of a high mutation rate, such as deleterious mutations, and the metabolic costs of maintaining systems to reduce the mutation rate, such as DNA repair enzymes. Viruses that use RNA as their genetic material have rapid mutation rates, which can be an advantage since these viruses will evolve constantly and rapidly, and thus evade the defensive responses of e.g. the human immune system.

Gulf of Mexico Oil Spill Blog Gulf Blue Plague Pandemic

Gulf Blue Plague Pandemic The Perfect Genetic Storm – Synthetic DNA and the Gulf Blue Plague By Michael Edward There’s a new proprietary recipe being force-fed to all of us here on the Gulf of Mexico that is now becoming … Continue reading

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Posted in Corexit, Gulf of Mexico Oil Spill, Microbes, Microbial Enhanced Oil Recovery, Mutation, Scientific Reports, Synthetic Genomics, Terry Hazen | Tagged , , , , , , , , , , , , , , , , | 3 Comments

Gulf of Mexico Oil Spill Blog Mutation

Mutation – Bearded Clams Professor sees hope in Gulf after oil spill By By Paul Mulvihill Chicagoans looking for fun in the sun historically flock to the Gulf Coast during winter. After the BP oil spill in April that lasted until … Continue reading

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